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Kinetics of gene expression in bacteria — From models to measurements, and back again

Le professeur Dennis Salahub a fait d'importantes contributions dans plusieurs domaines scientifiques. Vraisemblablement, la moins connue de ces contributions est celle sur l'étude de la cinétique de l'expression des gènes dans les procaryotes qui a conduit à un modèle stochastique différé ... mehr

Star mesogens — Synthesis and structural characterization using 1D and 2D solution NMR techniques and mesophase characterization

Utilisant des approches divergentes, on a réalisé des synthèses de nouveaux mésogènes en forme étoilée à base d'acide trimésique et des portions centrales portant des chaînes latérales symétriques se terminant par des groupes alcoxy. Les portions centrales et les chaînes latérales sont liée ... mehr

Hepcidin, show some self-control! How the hormone of iron metabolism regulates its own expression

Does the hormone of iron metabolism, hepcidin, exhibit 'self-control'? Hepcidin is a small, disulfide-rich peptide synthesized by the liver, which plays a keystone role in regulating systemic iron metabolism in mammals. Hepcidin acts by binding and triggering the lysosomal degradation of t ... mehr

Evidence for novel aspects of Nox4 oxidase regulation of mitochondrial function and peroxide generation in an endothelial cell model of senescence

Observations by Kozieł et al. reported in this issue of the Biochemical Journal suggest the existence of novel regulatory processes associated with new evidence for increased Nox4 (NAPDH oxidase 4) regulation of mitochondrial function in a cultured endothelial cell aging-induced senescence ... mehr

Structure of a dimeric crenarchaeal Cas6 enzyme with an atypical active site for CRISPR RNA processing

The competition between viruses and hosts is played out in all branches of life. Many prokaryotes have an adaptive immune system termed 'CRISPR' (clustered regularly interspaced short palindromic repeats) which is based on the capture of short pieces of viral DNA. The captured DNA is integ ... mehr

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Non-contact halogen lamp heating assisted LTP ionization miniature rectilinear ion trap: a platform for rapid on-site explosives analysis

A platform consisting of a halogen lamp, a low temperature plasma (LTP) probe, and a miniature rectilinear ion trap mass spectrometer (RIT-MS) has been constructed and evaluated to detect the organic and inorganic explosives on solid surfaces. This platform features two attractive character ... mehr

Potentiometric sensors using cotton yarns, carbon nanotubes and polymeric membranes

A simple and generalized approach to build electrochemical sensors for wearable devices is presented. Commercial cotton yarns are first turned into electrical conductors through a simple dyeing process using a carbon nanotubes ink. These conductive yarns are then partially coated with a sui ... mehr

Solution-cathode glow discharge – optical emission spectrometry using a compact spectrograph

A solution-cathode glow discharge is coupled to a compact spectrograph. Such a coupling results in a small, potentially portable instrument that can simultaneously detect a range of metals by optical emission spectrometry. Detection limits were calculated for Ag (1 ppb), Cd (2 ppb), Cu (8 p ... mehr

On-Line Microfluidic Device Coupled with Inductively Coupled Plasma Mass Spectrometry for Chromium Speciation

In this study, an on-line polyoxometalate cluster (POM)/microfluidic (MF) separation system coupled with inductively coupled plasma mass spectrometry (ICP-MS) detection was developed for the determination of trivalent [Cr(III)] and hexavalent [Cr(VI)] chromium species in aqueous samples. In ... mehr

Employing aqueous CdTe quantum dots with diversified surface functionalities to discriminate between heme (Fe(II)) and hemin (Fe(III))

The discrimination of ferrous and ferric states in the human body is one of the basic issues for disease control and prevention because Fe(ii) and Fe(iii) are a crucial redox pair during the process of material and energy metabolism. Herein, aqueous CdTe quantum dots (QDs) with diversified ... mehr

Alle Fachpublikationen zu Analytik

Kinetics of gene expression in bacteria — From models to measurements, and back again

Le professeur Dennis Salahub a fait d'importantes contributions dans plusieurs domaines scientifiques. Vraisemblablement, la moins connue de ces contributions est celle sur l'étude de la cinétique de l'expression des gènes dans les procaryotes qui a conduit à un modèle stochastique différé ... mehr

Star mesogens — Synthesis and structural characterization using 1D and 2D solution NMR techniques and mesophase characterization

Utilisant des approches divergentes, on a réalisé des synthèses de nouveaux mésogènes en forme étoilée à base d'acide trimésique et des portions centrales portant des chaînes latérales symétriques se terminant par des groupes alcoxy. Les portions centrales et les chaînes latérales sont liée ... mehr

Hepcidin, show some self-control! How the hormone of iron metabolism regulates its own expression

Does the hormone of iron metabolism, hepcidin, exhibit 'self-control'? Hepcidin is a small, disulfide-rich peptide synthesized by the liver, which plays a keystone role in regulating systemic iron metabolism in mammals. Hepcidin acts by binding and triggering the lysosomal degradation of t ... mehr

Evidence for novel aspects of Nox4 oxidase regulation of mitochondrial function and peroxide generation in an endothelial cell model of senescence

Observations by Kozieł et al. reported in this issue of the Biochemical Journal suggest the existence of novel regulatory processes associated with new evidence for increased Nox4 (NAPDH oxidase 4) regulation of mitochondrial function in a cultured endothelial cell aging-induced senescence ... mehr

Structure of a dimeric crenarchaeal Cas6 enzyme with an atypical active site for CRISPR RNA processing

The competition between viruses and hosts is played out in all branches of life. Many prokaryotes have an adaptive immune system termed 'CRISPR' (clustered regularly interspaced short palindromic repeats) which is based on the capture of short pieces of viral DNA. The captured DNA is integ ... mehr

Alle Fachpublikationen zu Chemie

Inside Lab Invest

Inside Lab Invest Laboratory Investigation 93, 500 (May 2013). doi:10.1038/labinvest.2013.58 mehr

Inside Lab Invest

Inside Lab Invest Laboratory Investigation 93, 376 (April 2013). doi:10.1038/labinvest.2013.49 mehr

Methods for defining distinct bioenergetic profiles in platelets, lymphocytes, monocytes, and neutrophils, and the oxidative burst from human blood

Methods for defining distinct bioenergetic profiles in platelets, lymphocytes, monocytes, and neutrophils, and the oxidative burst from human blood Laboratory Investigation advance online publication, March 25 2013. doi:10.1038/labinvest.2013.53 Authors: Balu K Chacko, Phili ... mehr

Inside Lab Invest

Inside Lab Invest Laboratory Investigation 93, 266 (March 2013). doi:10.1038/labinvest.2013.11 mehr

Hydroxylases as therapeutic targets in inflammatory bowel disease

Hydroxylases as therapeutic targets in inflammatory bowel disease Laboratory Investigation advance online publication, February 18 2013. doi:10.1038/labinvest.2013.9 Authors: Eoin P Cummins, Glen A Doherty & Cormac T Taylor mehr

Alle Fachpublikationen zu Labortechnik

Spray and packed liquid–liquid extraction columns: drop size and dispersed phase mass transfer

ABSTRACT The effects of holdup on Sauter mean drop diameter, D32, and dispersed phase mass transfer coefficient have been studied in the spray and packed extraction columns. For both columns, two well‐defined regions for the dependence of D32 on holdup were observed. D32 increased and d ... mehr

Kinetics of the dissolution of ilmenite in oxalic and sulfuric acid solutions

ABSTRACT In this study, the effects of particle size, type and concentration of acid solution on dissolution kinetics of ilmenite are investigated. The results showed that both oxalic and sulfuric acid and their concentrations had relatively high effects on the dissolution rate of titan ... mehr

Future Production Concepts in the Chemical Industry: Modular – Small‐Scale – Continuous

Abstract Modular continuous production concepts are already successfully applied in research, development, and piloting of a series of chemical compounds in the markets of fine chemistry and pharmaceutical products. Besides, first case studies for the application of those concepts in in ... mehr

Highly Controlled Gas/Liquid Processes in a Continuous Lab‐Scale Device

Abstract The use of reactive gases for syntheses on small laboratory scale is often avoided due to safety concerns so that expensive alternatives are required. The recent development of gas‐permeable membrane‐based reactors offers new options for safe handling of these gases in a contin ... mehr

Essential work of fracture analysis of short glass fiber and/or calcite reinforced ABS/PA6 composites

Abstract The effect of reinforcing agent type and composition on the fracture behavior of short glass fiber (SGF), CaCO3 particle, and glass fiber/CaCO3 hybrid reinforced ABS/PA6 blend based composites have been studied by using the essential work of fracture (EWF) method. Two millimete ... mehr

Alle Fachpublikationen zu Verfahrenstechnik

A new immunoassay to quantify fungal antigens from the indoor mould Aspergillus versicolor

Aspergillus versicolor is among the most commonly found moulds in moisture-damaged buildings and can be associated with adverse health effects in humans. This paper reports the development, validation and application of an enzyme immunoassay to quantify A. versicolor antigens. A sandwich EL ... mehr

Cadmium uptake, chemical forms, subcellular distribution, and accumulation in Echinodorus osiris Rataj

Phytoremediation is a technology for extracting or inactivating pollutants in soil. Echinodorus osiris(E.osiris) is a fast growing perennial wetland plant that is common in tropical and subtropical areas and has a high tolerance to cadmium (Cd). However, the absorption dynamic, subcellular ... mehr

Environmental fate of processed natural rubber latex

In this study, processed natural rubber latex was degraded in outdoor aquatic microcosms, under a number of treatment scenarios for 200 days. The analytical strategy adopted aimed to characterise a range of volatile, semi-volatile and non-volatile substances. Zinc, was shown to migrate from ... mehr

Quantitative and Qualitative Sensing Techniques for Biogenic Volatile Organic Compounds and Their Oxidation Products

The physiological production mechanisms of some of the organics in plants, commonly known as biogenic volatile organic compounds (BVOCs) have been known for more than a century. Some BVOCs are emitted to the atmosphere and play a significant role in tropospheric photochemistry especially in ... mehr

Responses of Fraxinus exelsiors L. seedlings to ambient ozone exposure at urban and mountain areas based on some physiological characteristics and antioxidant activity

The possible effects of ozone on the sensitive tree species Fraxinus exelsiors L. exposed to ambient air were investigated. The dynamics of photosynthesis, transpiration, stomatal conductance and activity of the antioxidant enzymes superoxide dismutase (SOD) and catalase (CAT) in three-year ... mehr

Alle Fachpublikationen zu Umwelttechnik
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