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Aktuelle Fachpublikationen

A human intestinal M-cell-like model for investigating particle, antigen and microorganism translocation

Nature Protocols 12, 1387 (2017). doi:10.1038/nprot.2017.041 Authors: Ana Beloqui, David J Brayden, Per Artursson, Véronique Préat & Anne des Rieux The specialized microfold cells (M cells) in the follicle-associated epithelium (FAE) of intestinal Peyer's patches serve as ... mehr

Preparation of biomimetic hierarchically helical fiber actuators from carbon nanotubes

Nature Protocols 12, 1349 (2017). doi:10.1038/nprot.2017.038 Authors: Jue Deng, Yifan Xu, Sisi He, Peining Chen, Luke Bao, Yajie Hu, Bingjie Wang, Xuemei Sun & Huisheng Peng Mechanically responsive materials that are able to sense and respond to external stimuli have impo ... mehr

Integrating macromolecular X-ray diffraction data with the graphical user interface iMosflm

Nature Protocols 12, 1310 (2017). doi:10.1038/nprot.2017.037 Authors: Harold R Powell, T Geoff G Battye, Luke Kontogiannis, Owen Johnson & Andrew G W Leslie X-ray crystallography is the predominant source of structural information for biological macromolecules, providing ... mehr

Enantioselective gold(I)-catalyzed rearrangement of cyclopropyl-substituted 1,6-enynes into 2-oxocyclobutyl-cyclopentanes

A gold(i)-catalyzed cycloisomerization/ring expansion sequence allows the highly enantioselective synthesis of 2-oxocyclobutylcyclopentane derivatives from cyclopropyl-substituted enynes. The bimetallic [(R)-MeO-DTBM-BIPHEP-(AuCl)2] complex was found to be the best precatalyst, affording th ... mehr

Upconversion based near white light emission, intrinsic optical bistability and temperature sensing in Er3+/Tm3+/Yb3+/Li+: NaZnPO4 phosphors

NaZnPO4: Er3+/Tm3+/Yb3+/Li+ phosphors successfully synthesized by conventional solid state reaction method have been characterized through XRD, FESEM, EDAX, diffuse reflectance spectra and FTIR analysis. Downconversion (DC) and upconversion (UC) emission study of developed phosphors have be ... mehr

Alle Fachpublikationen

Automated and controlled mechanical stimulation and functional imaging in vivo in C. elegans

C. elegans is a useful genetic model system for investigating mechanisms involved in sensory behavior, potentially relevant to human diseases. While utilities of advanced techniques such as microfluidics have accelerated some areas of C. elegans sensory biology such as chemosensation, studi ... mehr

Thiol–ene micropillar array electrospray ionization platform for zeptomole level bioanalysis

A micropillar array electrospray ionization (μPESI) platform fabricated from thiol–enes with 56 individual polyethylene glycol coated μPESI chips for bioanalytical mass spectrometry is introduced. Bioanalysis capability is shown by measurement of a protein, a protein digest and a cell lysat ... mehr

Reply to the ‘Comment on “Robust scalable high throughput production of monodisperse drops”’ by M. Nakajima, Lab Chip, 2017, 17, DOI: 10.1039/C7LC00181A

This reply to the comment by Nakajima on our article that appeared in Lab on a Chip (E. Amstad, M. Chemama, M. Eggersdorfer, L. R. Arriaga, M. Brenner and D. A. Weitz, Lab Chip, 2016, 16, 4163–4172) highlights the differences between the microchannel step emulsification devices developed by ... mehr

A precise and accurate microfluidic droplet dilutor

We demonstrate a microfluidic system for precise (coefficient of variance between repetitions below 4 %) and highly accurate (average difference from two-fold dilution below 1 %) serial dilution of solutions inside droplets with a volume of ca. 1 µl. The two-fold dilution series can be prep ... mehr

Fluorescent miRNA analysis enhanced by mesopore effects of polydopamine nanoquenchers

The combination of fluorophore-labelled single-strand DNA probes and nanomaterial quenchers has shown great potential in miRNA detection. The development of advanced detection systems by understanding and controlling the fluorescence quenching/recovery via nanoquenchers’ microstructures and ... mehr

Alle Fachpublikationen zu Analytik

Enantioselective gold(I)-catalyzed rearrangement of cyclopropyl-substituted 1,6-enynes into 2-oxocyclobutyl-cyclopentanes

A gold(i)-catalyzed cycloisomerization/ring expansion sequence allows the highly enantioselective synthesis of 2-oxocyclobutylcyclopentane derivatives from cyclopropyl-substituted enynes. The bimetallic [(R)-MeO-DTBM-BIPHEP-(AuCl)2] complex was found to be the best precatalyst, affording th ... mehr

Upconversion based near white light emission, intrinsic optical bistability and temperature sensing in Er3+/Tm3+/Yb3+/Li+: NaZnPO4 phosphors

NaZnPO4: Er3+/Tm3+/Yb3+/Li+ phosphors successfully synthesized by conventional solid state reaction method have been characterized through XRD, FESEM, EDAX, diffuse reflectance spectra and FTIR analysis. Downconversion (DC) and upconversion (UC) emission study of developed phosphors have be ... mehr

Facile synthesis of a heterogeneous Li2TiO3/TiO2 nanocomposite with enhanced photoelectrochemical water splitting

A heterogeneous Li2TiO3/TiO2 nanocomposite was successfully prepared from anodized amorphous TiO2 nanotube arrays in CH3COOLi solution by using a facile hydrothermal method. Morphology transformation from nanotubes into diamond-shaped nanoparticles can be attributed to the water-induced dis ... mehr

A Coherent study on the Z-enoate assisted Meyer-Schuster rearrangement

A systematic study has been performed on the Z-enoate assisted Meyer-Schuster rearrangement of propargylic alcohols. Impact of various factors such as temperature, solvent, concentration of counter ion of acid, and nature of the arene nucleophile was studied. The relative nucleophilicity of ... mehr

Experimental evidence of 3-centre, 2-electron covalent bond character of the central O-H-O fragment on the Zundel cation in crystals of Zundel nitranilate tetrahydrate

Charge density of the Zundel cationin the crystal of 2[H5O2]+[C6O8 N2]-∙4H2O, is studied by X-ray diffraction and periodic DFT calculations. Covalent nature of the central O-H-O bonds in the Zundel cation is revealed: electron density at the two O-H critical points is about 1.0 eÅ-3, corres ... mehr

Alle Fachpublikationen zu Chemie

Malignant melanoma: from cause to cure

Malignant melanoma: from cause to cure Laboratory Investigation 97, 628 (June 2017). doi:10.1038/labinvest.2017.57 mehr

Inside the USCAP Journals

Inside the USCAP Journals Laboratory Investigation 97, 492 (May 2017). doi:10.1038/labinvest.2017.38 mehr

The evolving concept of cancer stem-like cells in thyroid cancer and other solid tumors

The evolving concept of cancer stem-like cells in thyroid cancer and other solid tumors Laboratory Investigation advance online publication, April 10 2017. doi:10.1038/labinvest.2017.41 Authors: Heather Hardin, Ranran Zhang, Holly Helein, Darya Buehler, Zhenying Guo & Ricardo ... mehr

Inside the USCAP Journals

Inside the USCAP Journals Laboratory Investigation 97, 354 (April 2017). doi:10.1038/labinvest.2017.27 mehr

T-lymphocyte homing: an underappreciated yet critical hurdle for successful cancer immunotherapy

T-lymphocyte homing: an underappreciated yet critical hurdle for successful cancer immunotherapy Laboratory Investigation advance online publication, March 27 2017. doi:10.1038/labinvest.2017.25 Authors: Robert Sackstein, Tobias Schatton & Steven R Barthel mehr

Alle Fachpublikationen zu Labortechnik

Tunable physicochemical properties of PVA nanocomposite membranes for enhanced pervaporation performance

This study reveals the effect of hydrophilic bentonite nanoclay on the pervaporation separation of azeotropic composition of water and 1,4‐dioxane. The permselectivity of the membrane increased with filler concentration and was selective toward water at minimum filler loading. The intrinsic ... mehr

Comprehensive study on the relationships between the processing, the microstructure, and mechanical properties of injection molded polypropylenes

The relationship between the morphologies of different injection molded polypropylenes and their tensile properties measured at high strain rate were investigated. A threefold systematic analysis is proposed by establishing the following relationships: (i) processing‐morphology; (ii) proces ... mehr

Modification of polyoxymethylene for increased thermal resistance

Ternary nanocomposites, composed of polyoxymethylene (POM), ethylene octene copolymer and zinc oxide (ZnO), are prepared by melt compounding. The effects of two types of ethylene‐octene copolymers, differing with α‐octene content (38% for EOC38 and 17% for EOC17), as well as nanostructured ... mehr

Preparation and in Vitro Evaluation of Hydrophobic‐Modified Montmorillonite Stabilized Pickering Emulsion for Overdose Acetaminophen Removal

ABSTRACT Pickering emulsion stabilized with hydrophobic‐modified montmorillonite (HMMT) was proposed for treating acute overdose acetaminophen intoxication, with a rapid removal rate, better stability, and good biocompatibility. The tiny HMMT was able to adsorb at the oil‐water interfac ... mehr

Covariance Eigenpairs Neighbor Distance for Fault Detection in Chemical Processes

Abstract This paper presents a new data‐driven fault detection method called covariance eigenpairs neighbor distance (CEND) for monitoring chemical processes. It processes measured data in one‐step sliding windows to estimate covariance, and the eigenpairs of each sample covariance matr ... mehr

Alle Fachpublikationen zu Verfahrenstechnik

Impact of the Composition of the Bacterial Population and Additional Carbon Source on Pathway and Kinetics of Degradation of Endosulfan Isomers

Abiotic and bacterial degradation is presented for the two isomers α- and β- of the organochlorine pesticide endosulfan, denoted as ES-1 and ES-2, respectively. Biodegradation studies were conducted with two indigenous species Pseudomonas Putida (P. putida) and Rhodococcus sp. Both the ES i ... mehr

High throughput in vitro and in vivo screening of inland waters of Southern California

The impact of unmonitored contaminants, also known as contaminants of emerging concern (CECs), on freshwater streams remains largely uncharacterized. Water samples from 31 streams representing urban, agricultural and undeveloped (i.e., open space) land use in Southern California (USA) were ... mehr

IJERPH, Vol. 14, Pages 654: Assessing Statistically Significant Heavy-Metal Concentrations in Abandoned Mine Areas via Hot Spot Analysis of Portable XRF Data

To develop appropriate measures to prevent soil contamination in abandoned mining areas, an understanding of the spatial variation of the potentially toxic trace elements (PTEs) in the soil is necessary. For the purpose of effective soil sampling, this study uses hot spot analysis, which ca ... mehr

IJERPH, Vol. 14, Pages 653: Association between Six CETP Polymorphisms and Metabolic Syndrome in Uyghur Adults from Xinjiang, China

Objective: To explore the association between CETP gene polymorphisms and metabolic syndrome (MS), as well as the relationship between the CETP gene polymorphisms and each component of MS. Methods: A total of 571 individuals which were randomly selected from 5692 Uyghur adults were subdivid ... mehr

Sustainability, Vol. 9, Pages 1057: Technology Credit Scoring Based on a Quantification Method

Credit scoring models are usually formulated by fitting the probability of loan default as a function of individual evaluation attributes. Typically, these attributes are measured using a Likert-type scale, but are treated as interval scale explanatory variables to predict loan defaults. Ex ... mehr

Alle Fachpublikationen zu Umwelttechnik
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