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Synthesis of pyrrolo[1,2 a]naphthyridines by Lewis acid mediated cycloisomerization

Pyrrolo[1,2-a]naphthyridines were synthesized from 3 alkynyl-2 ([1H] pyrrol 1 yl)pyridines and 3 alkynyl 4-([1H] pyrrol 1 yl)pyridines by cycloisomerization. The reactions are performed by application of the Lewis acids PtCl2 or Bi(OTf)3 without the need of further additives. With the described methods a num

Autoren:   Anika Flader; Silvio Parpart; Peter Ehlers; Peter Langer
Journal:   Organic & Biomolecular Chemistry
DOI:   10.1039/C7OB00343A
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