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Metal-free synthesis of isatin oximes via radical coupling reactions of oxindoles with t-BuONO in water

A metal-free method for the synthesis of isatin oximes was developed through the radical coupling reactions of oxindoles with t-BuONO. This protocol provides a practical and environmentally benign method for the construction of C–N bonds in water at room temperature without using any other reagents. The advantages

Autoren:   Wen-Ting Wei; Wen-Ming Zhu; Wei-Wei Ying; Yi Wu; Yi-Ling Huang; Hongze Liang
Journal:   Organic & Biomolecular Chemistry
DOI:   10.1039/C7OB01235G
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