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Synthesis and in vitro phototoxicity of novel [small pi]-extension derivatives of chlorin e6

Six novel E-32-aryl substituted chlorins (5a–5f) were synthesized via improved regioselective bromination and Suzuki–Miyaura cross-coupling reactions with chlorin e6 (1) as a starting material. All the π-extension photosensitizers 5a–5f exhibited significant bathochromic-shifts (ca. 10 nm) in the far red part of th

Autoren:   Lei Cao; Xiuhan Guo; Liu Wang; Shisheng Wang; Yueqing Li; Weijie Zhao
Journal:   New Journal of Chemistry
DOI:   10.1039/C7NJ03279J
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