NO is a key vasodilator in mammalian cardiovascular systems and has been shown to sensitize tissue to γ‐radiation. However, photochemical NO precursors that can be activated by these NIR wavelengths are extremely limited. G. D. Stucky, D. Zhao, P. C. Ford, F. Zhang and co‐workers have addressed this issue by utilizing the known NIR to visible upconversion properties of lanthanide‐doped NaYF4 nanocrystals. This result, described on page 3800, is a potential game changer in multiphoton excitation‐based therapeutic delivery of NO and other small molecule bioregulators to physiological targets.
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| Autoren: |
|
John V. Garcia, Jianping Yang, Dengke Shen, Chi Yao, Xiaoming Li, Rui Wang, Galen D. Stucky, Dongyuan Zhao, Peter C. Ford, Fan Zhang |
| Journal: |
|
Small
|
| Band: |
|
8 |
| Ausgabe: |
|
24 |
| Jahrgang: |
|
2012 |
| Seiten: |
|
3701 |
| DOI: |
|
10.1002/smll.201290136 |
| Erscheinungsdatum: |
|
15.12.2012 |