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49.451 Aktuelle Fachpublikationen aus der Branche Analytik


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Flocculation on a chip: a novel screening approach to determine floc growth rates and select flocculating agents

24.01.2018 | Anand N. P. Radhakrishnan; Marco P. C. Marques; Matthew J. Davies; Brian O'Sullivan; Daniel G. Bracewell; Nicola ..., Lab on a Chip, 2018

Flocculation is a key purification step in cell-based processes for the food and pharmaceutical industry where the removal of cells and cellular debris is aided by adding flocculating agents. However, finding the best suited flocculating agent and optimal conditions to achieve rapid and effective ...


Rapid and sensitive detection of neuron specific enolase with a polydopamine coated plasmonic chip utilizing a rear-side coupling method

24.01.2018 | M. Toma; S. Izumi; K. Tawa, Analyst, 2018

A rapid and sensitive detection of a cancer marker, neuron specific enolase (NSE), is demonstrated by using a disposable silver plasmonic chip functionalized with a mussel-inspired polydopamine (PDA) coating. A plasmonic chip consisting of a diffraction grating coated with a silver thin film is ...


Turn-on near-infrared fluorescence probe with aggregation-induced emission based on dibenzo[a,c]phenazine for detection of superoxide anions and its application in cell imaging

24.01.2018 | Jianli Hua; Ji Yang; Xianglong Liu; Honglei Wang; Haoqi Tan; Xiaoxu Xie; Xiao Zhang; Chenchen Liu; Xue Qu, Analyst, 2018

A new turn-on near-infrared fluorescence probe (BDP) based on dibenzo[a,c]phenazine for superoxide anions detection with aggregation-induced emission property as well as a desirable large Stokes shift was designed and synthesized. After the reaction with superoxide, the initial ...


High-Throughput Sorting of Eggs for Synchronization of C. elegans in a Microfluidic Spiral Chip

24.01.2018 | Samuel Sofela; Sarah Sahloul; Mehdi Rafeie; Taehong Kwon; Majid Ebrahimi Warkiani; Jongyoon Han; Yong-Ak Song, Lab on a Chip, 2018

In this study, we report the use of a high-throughput microfluidic spiral chip to screen out eggs from a mixed age nematode population, which can subsequently be cultured to a desired developmental stage. For the sorting of a mixture containing three different developmental stages, eggs, L1 and ...


15N isotopic labelling for in-cell protein studies by NMR spectroscopy and single-cell IR Synchrotron Radiation FTIR Microscopy: a correlative study

24.01.2018 | Elisa Mitri; Letizia Barbieri; Lisa Vaccari; Enrico Luchinat, Analyst, 2018

The ultimate goal of modern structural biology is to probe proteins structure and dynamics in their physiological microenvironment. In-cell NMR spectroscopy is an ideal technique for achieving this goal, being able to investigate proteins at atomic-resolution in living cells. The reliability of ...


Rapid Screening of Gas Catalysts in Methane Activation Using ICP-QQQ-MS

24.01.2018 | Qian He; Jiajia Wu; Sichun Zhang; Xiang Fang; Zhi Xing; Chao Wei; Xinrong Zhang, Journal of Analytical Atomic Spectrometry, 2018

A novel platform for rapid screening of gas catalysts in methane activation using ICP-QQQ-MS was developed. The gas ions catalysts could be produced in ICP torch from the bulk solution. The dynamic reaction cell in ICP-QQQ-MS could be used as the reactor to mix methane with the gas ions catalyst ...


Time-resolved visual detection of heparin by accelerated etching of gold nanorods

24.01.2018 | Jian Wang; Hong Zhi Zhang; Jia Jun Liu; Dan Yuan; Rong Sheng Li; Cheng Zhi Huang, Analyst, 2018

Plasmonic gold nanorods are promising and sensitive light scattering probes, which can reach the single particle level. Herein, we present the light scattering property of gold nanorods for time-resolved visual detection of heparin based on the rapid etching of gold nanorods under dark-field ...


Direct Thermal Desorption Gas Chromatographic Determination of Toxicological Relevant Concentrations of Ethylene Glycol in Whole Blood

23.01.2018 | James Robson; Stephen Townsend; Paul Bowdler; K C Honeychurch, Analyst, 2018

A simple and rapid method involving thermal-desorption gas chromatography with flame ionisation detection (TD-GC) has been successfully developed for the determination of ethylene glycol in whole blood. No sample extraction or derivatization steps were required. The conditions required for the ...


Detection of Prostate Specific Antigen (PSA) in Human Saliva Using an Ultra-Sensitive Nanocomposite of Graphene Nanoplatelet with Diblock-co-Polymer and Au Electrodes

23.01.2018 | Muhammad Shuja Khan; Ketan Dighe; Zhen Wang; Indrajit Srivastava; Enrique Daza; Aaron Star Schwartz-Duval; Jamil Gha ..., Analyst, 2018

Prostate-specific antigen (PSA) is a commonly used biomarker for the detection of prostate cancer (PCa) and there are numerous data available for its invasive detection in serum and whole blood. In this work, an electrochemical sensing method was devised to detect the traces of PSA in human ...


Identification of Isoforms of Aspartic Acid Residue in Peptides by 2D UV-MS Fingerprinting of Cold Ions

23.01.2018 | Vladimir Kopysov; Mikhail V Gorshkov; Oleg V Boyarkin, Analyst, 2018

We use 2D UV-MS cold-ion spectroscopy for identifications of L-Asp, D-Asp, L-isoAsp and D-isoAsp residues in a fragment peptide derived from hormon protein amylin. Relative solution concentrations of all four isoforms in an equimolar quaternary mixture have been determined within 4% error. The ...


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