17.10.2013 | A. Shanavas, T. Narasimhaswamy, B.V.N. Phani Kumar, A. Sultan Nasar, Canadian Journal of Chemistry, 2013

Utilisant des approches divergentes, on a réalisé des synthèses de nouveaux mésogènes en forme étoilée à base d'acide trimésique et des portions centrales portant des chaînes latérales symétriques se terminant par des groupes alcoxy. Les portions centrales et les chaînes latérales sont liées ...

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15.04.2013 | Bett JS; Ibrahim AFM; Garg AK; Kelly V; Pedrioli P; Rocha S; Hay RT, Biochemical Journal, 2013

HIF1A (hypoxia-inducible factor 1α) is the master regulator of the cellular response to hypoxia and is implicated in cancer progression. Whereas the regulation of HIF1A protein in response to oxygen is well characterized, less is known about the fate of HIF1A mRNA. In the present study, we ...

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15.04.2013 | Sundberg EJ, Biochemical Journal, 2013

Asthma is a debilitating chronic inflammatory disease of the airways that results in shortness of breath, wheezing and coughing, often triggered by inhalation of common allergens. The prevalence and severity of asthma has increased dramatically over the last several decades to the point ...

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15.04.2013 | Zhou C; Zhou Y; Wang J; Feng Y; Wang H; Xue J; Chen Y; Ye RD; Wang M-W, Biochemical Journal, 2013

Genetic variation plays a major role in drug response variability. CsA (cyclosporin A), a widely used immunosuppressive agent, is a specific antagonist for FPR1 (formyl peptide receptor 1), which is an important G-protein-coupled chemoattractant receptor in the innate immune system. In order ...

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15.04.2013 | Hindley C; Philpott A, Biochemical Journal, 2013

PSCs (pluripotent stem cells) possess two key properties that have made them the focus of global research efforts in regenerative medicine: they have unlimited expansion potential under conditions which favour their preservation as PSCs and they have the ability to generate all somatic cell ...

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15.04.2013 | Khan SA; Rossi AM; Riley AM; Potter BVL; Taylor CW, Biochemical Journal, 2013

IP3R (IP3 [inositol 1,4,5-trisphosphate] receptors) and ryanodine receptors are the most widely expressed intracellular Ca2+ channels and both are regulated by thiol reagents. In DT40 cells stably expressing single subtypes of mammalian IP3R, low concentrations of thimerosal (also known as ...

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10.04.2013 | Mitsuaki Yamauchi; Shun Kubota; Takashi Karatsu; Akihide Kitamura; Ayyappanpillai Ajayaghosh; Shiki Yagai, Chemical Communication, 2013

Bismelamines end-functionalized with oligo(p-phenylenevinylene) self-aggregate in nonpolar solvent to form short nanorods by helical π-π stacking. This inherent self-aggregation can be guided to a supramolecular polymerization pathway by complexing with a cyanurate, leading to gel-forming ...

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10.04.2013 | Dominik K. Kölmel; Birgit Rudat; Delia Braun; Christin Bednarek; Ute Schepers; Stefan Bräse, Organic & Biomolecular Chemistry, 2013

Incorporation of fluorous ponytails such as polyfluorinated alkyl residues (CH2)m(CF2)nCF3 leads to a novel class of bright rhodamine-based fluorescence dyes. These dyes combine the excellent photophysical properties of the frequently used rhodamine dyes with the unique features of “light” ...

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10.04.2013 | Lijia Liu; Tsun-Kong Sham; Weiqiang Han, Physical Chemistry Chemical Physics, 2013

Graphene-like BN nanosheets were synthesized via carbon-substitution reaction using graphene as a template in an attempt to produce C-doped BN. The carbon residue was removed by high-temperature oxidation in air. The role of the graphene template and oxygen with regard to the local structure ...

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10.04.2013 | Zhaofei Chen; Haiyan An; Hua Zhang; Ying Hu, CrystEngComm, 2013

Six new hybrid species based on amino acid functionalized γ-octamolybdates, [(H2O)3M]2[Mo8O26(pro)2]•2H2O (M = Cu 1, Zn 2, Co 3), [(H2O)8(lys)2Cu3][Mo8O27]•12H2O (4), [(H2O)6M][Mo8O26(lysH)2]•4H2O (M= Zn 5, Co 6) (pro = proline; lys, lysH = lysine), have been synthesized and characterized by ...

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