05.04.2013 | Saija Haapa-Paananen et al., PLoS ONE, 2013

by Saija Haapa-Paananen, Ping Chen, Kirsi Hellström, Pekka Kohonen, Sampsa Hautaniemi, Olli Kallioniemi, Merja Perälä Cancer initiation and progression involve microRNAs that can function like tumor suppressors and oncogenes. The functional significance of most miRNAs is currently ...

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05.04.2013 | Toshiyasu Goto et al., PLoS ONE, 2013

by Toshiyasu Goto, Atsushi Sato, Masahiro Shimizu, Shungo Adachi, Kiyotoshi Satoh, Shun-ichiro Iemura, Tohru Natsume, Hiroshi Shibuya Dishevelled (DVL) is a central factor in the Wnt signaling pathway, which is highly conserved among various organisms. DVL plays important roles in ...

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05.04.2013 | Azadeh Kushki et al., PLoS ONE, 2013

by Azadeh Kushki, Ellen Drumm, Michele Pla Mobarak, Nadia Tanel, Annie Dupuis, Tom Chau, Evdokia Anagnostou Assessment of anxiety symptoms in autism spectrum disorders (ASD) is a challenging task due to the symptom overlap between the two conditions as well as the difficulties in ...

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05.04.2013 | Zhongqin Yang et al., PLoS ONE, 2013

by Zhongqin Yang, Bihe Hu, Yuhui Zhang, Qingming Luo, Hui Gong Fluorescent proteins serve as important biomarkers for visualizing both subcellular organelles in living cells and structural and functional details in large-volume tissues or organs. However, current techniques for ...

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05.04.2013 | Andras Jakab et al., PLoS ONE, 2013

by Andras Jakab, Monika Beres, Ervin Berenyi, Miklos Emri, Tamas Spisak, Sandor Attila Kis, Anita Szeman-Nagy, Peter Molnar Attempts to explicate the neural abnormalities behind autism spectrum disorders frequently revealed impaired brain connectivity, yet our knowledge is limited ...

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05.04.2013 | Stephan Raphael Rieder et al., PLoS ONE, 2013

by Stephan Raphael Rieder, Ivano Brunner, Otto Daniel, Bian Liu, Beat Frey Methylmercury compounds are very toxic for most organisms. Here, we investigated the potential of earthworms to methylate inorganic-Hg. We hypothesized that the anaerobic and nutrient-rich conditions in the ...

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05.04.2013 | Lei Sun et al., PLoS ONE, 2013

by Lei Sun, Xiaowei Yang, Feifei Chen, Rongpeng Li, Xuesong Li, Zhenxing Liu, Yuyu Gu, Xiaoyan Gong, Zhonghua Liu, Hua Wei, Ying Huang, Sheng Yuan Fission yeast cells express Rpl32-2 highly while Rpl32-1 lowly in log phase; in contrast, expression of Rpl32-1 raises and reaches a ...

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05.04.2013 | Russell E. Jackson et al., PLoS ONE, 2013

by Russell E. Jackson, Chéla R. Willey, Lawrence K. Cormack Most behaviors are conditional upon successful navigation of the environment, which depends upon distance perception learned over repeated trials. Unfortunately, we understand little about how learning affects distance ...

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05.04.2013 | Alexander Chi et al., PLoS ONE, 2013

by Alexander Chi, Pan Ma, Guishan Fu, Gerry Hobbs, James S. Welsh, Nam P. Nguyen, Si Young Jang, Jinrong Dai, Jing Jin, Ritsuko Komaki Background Helical tomotherapy (HT) and volumetric modulated arc therapy (VMAT) are both advanced techniques of delivering intensity-modulated radiotherapy ...

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05.04.2013 | Sarah J. Denton et al., PLoS ONE, 2013

by Sarah J. Denton, Michael I. Trenell, Thomas Plötz, Louise A. Savory, Daniel P. Bailey, Catherine J. Kerr Background Sedentary behaviour is a major risk factor for developing chronic diseases and is associated with low cardiorespiratory fitness in adults. It remains unclear how sedentary ...

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