18.06.2012 | André M. Striegel; Amandaa K. Brewer, Annual Review of Analytical Chemistry, 2012

Hydrodynamic chromatography (HDC) has experienced a resurgence in recent years for particle and polymer characterization, principally because of its coupling to a multiplicity of physical detection methods. When coupled to light scattering (both multiangle static and quasi-elastic), ...

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18.06.2012 | Torsten C. Schmidt; Maik A. Jochmann, Annual Review of Analytical Chemistry, 2012

Within the past 15 years, compound-specific stable isotope analysis has continued to increase in popularity in the area of contaminant hydrology of organic molecules. In particular, in cases where concentration data alone are insufficient to elucidate environmental processes unequivocally, ...

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18.06.2012 | Laralynne Przybyla; Joel Voldman, Annual Review of Analytical Chemistry, 2012

Although stem cell fate is traditionally manipulated by exogenously altering the cells' extracellular signaling environment, the endogenous autocrine and paracrine signals produced by the cells also contribute to their two essential processes: self-renewal and differentiation. Autocrine ...

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18.06.2012 | Barbara H. Berrie, Annual Review of Analytical Chemistry, 2012

Following a brief overview of the history of analysis of artists' pigments, I discuss the illustrative example of lead-tin yellow. Recent advances in our knowledge of artists' use of red lakes, glassy pigments, and metallic pigments in works of cultural heritage, particularly European ...

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18.06.2012 | H. Zänker; A. Schierz, Annual Review of Analytical Chemistry, 2012

The more nanotechnology develops, the more likely the release of engineered nanoparticles into the environment becomes. Due to a huge excess of natural nanoparticles, the identification and quantification of engineered nanoparticles pose a big challenge to analysts. Moreover, identification ...

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18.06.2012 | Bryant Gipson; David Hsu; Lydia E. Kavraki; Jean-Claude Latombe, Annual Review of Analytical Chemistry, 2012

Physics-based simulation represents a powerful method for investigating the time-varying behavior of dynamic protein systems at high spatial and temporal resolution. Such simulations, however, can be prohibitively difficult or lengthy for large proteins or when probing the lower-resolution, ...

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18.06.2012 | Shona Stewart; Ryan J. Priore; Matthew P. Nelson; Patrick J. Treado, Annual Review of Analytical Chemistry, 2012

The past decade has seen an enormous increase in the number and breadth of imaging techniques developed for analysis in many industries, including pharmaceuticals, food, and especially biomedicine. Rather than accept single-dimensional forms of information, users now demand multidimensional ...

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18.06.2012 | Richard N. Zare, Annual Review of Analytical Chemistry, 2012

Laser-induced fluorescence (LIF) is a spectroscopic technique that involves the excitation of a molecular target by a beam of laser radiation followed by the detection of the subsequent emission of radiation from the target. LIF detection has several advantages over absorption spectroscopy. ...

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18.06.2012 | Robin L. McCarley, Annual Review of Analytical Chemistry, 2012

Stimuli-responsive systems for the transport and delivery of materials to a given location at a specific time are highly valuable in numerous applications. The characteristics of the delivery system are dictated by the requirements of a particular application, which include the nature of the ...

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18.06.2012 | Shuo-Hui Cao; Wei-Peng Cai; Qian Liu; Yao-Qun Li, Annual Review of Analytical Chemistry, 2012

Surface plasmon–coupled emission (SPCE) arose from the integration of fluorescence and plasmonics, two rapidly expanding research fields. SPCE is revealing novel phenomena and has potential applications in bioanalysis, medical diagnostics, drug discovery, and genomics. In SPCE, excited ...

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