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26.146 Aktuelle Fachpublikationen in Proceedings of the National Academy of Sciences current issue

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Auxin steers root cell expansion via apoplastic pH regulation in Arabidopsis thaliana [Plant Biology]

13.06.2017 | Elke Barbez; Kai Dünser; Angelika Gaidora; Thomas Lendl; Wolfgang Busch, Proceedings of the National Academy of Sciences current issue, 2017

Plant cells are embedded within cell walls, which provide structural integrity, but also spatially constrain cells, and must therefore be modified to allow cellular expansion. The long-standing acid growth theory postulates that auxin triggers apoplast acidification, thereby activating cell ...

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Myosin Va’s adaptor protein melanophilin enforces track selection on the microtubule and actin networks in vitro [Biochemistry]

13.06.2017 | Angela Oberhofer; Peter Spieler; Yuliya Rosenfeld; Willi L. Stepp; Augustine Cleetus; Alistair N. Hume; Felix Muelle ..., Proceedings of the National Academy of Sciences current issue, 2017

Pigment organelles, or melanosomes, are transported by kinesin, dynein, and myosin motors. As such, melanosome transport is an excellent model system to study the functional relationship between the microtubule- and actin-based transport systems. In mammalian melanocytes, it is well known that ...

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Contacts between the endoplasmic reticulum and other membranes in neurons [Neuroscience]

13.06.2017 | Yumei Wu; Christina Whiteus; C. Shan Xu; Kenneth J. Hayworth; Richard J. Weinberg; Harald F. Hess; Pietro De Camilli, Proceedings of the National Academy of Sciences current issue, 2017

Close appositions between the membrane of the endoplasmic reticulum (ER) and other intracellular membranes have important functions in cell physiology. These include lipid homeostasis, regulation of Ca2+ dynamics, and control of organelle biogenesis and dynamics. Although these membrane contacts ...

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Postglacial response of Arctic Ocean gas hydrates to climatic amelioration [Earth, Atmospheric, and Planetary Sciences]

13.06.2017 | Pavel Serov; Sunil Vadakkepuliyambatta; Jürgen Mienert; Henry Patton; Alexey Portnov; Anna Silyakova; Giuliana Panie ..., Proceedings of the National Academy of Sciences current issue, 2017

Seafloor methane release due to the thermal dissociation of gas hydrates is pervasive across the continental margins of the Arctic Ocean. Furthermore, there is increasing awareness that shallow hydrate-related methane seeps have appeared due to enhanced warming of Arctic Ocean bottom water during ...

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Rifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations [Microbiology]

13.06.2017 | Kohta Saito; Thulasi Warrier; Selin Somersan-Karakaya; Lina Kaminski; Jianjie Mi; Xiuju Jiang; Suna Park; Kristi Shi ..., Proceedings of the National Academy of Sciences current issue, 2017

Mycobacterium tuberculosis (Mtb) encounters stresses during the pathogenesis and treatment of tuberculosis (TB) that can suppress replication of the bacteria and render them phenotypically tolerant to most available drugs. Where studied, the majority of Mtb in the sputum of most untreated ...

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Deciphering the landscape of host barriers to Listeria monocytogenes infection [Microbiology]

13.06.2017 | Ting Zhang; Sören Abel; Pia Abel zur Wiesch; Jumpei Sasabe; Brigid M. Davis; Darren E. Higgins; Matthew K. Waldor, Proceedings of the National Academy of Sciences current issue, 2017

Listeria monocytogenes is a common food-borne pathogen that can disseminate from the intestine and infect multiple organs. Here, we used sequence tag-based analysis of microbial populations (STAMP) to investigate L. monocytogenes population dynamics during infection. We created a genetically ...

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Altered interactions between unicellular and multicellular genes drive hallmarks of transformation in a diverse range of solid tumors [Systems Biology]

13.06.2017 | Anna S. Trigos; Richard B. Pearson; Anthony T. Papenfuss; David L. Goode, Proceedings of the National Academy of Sciences current issue, 2017

Tumors of distinct tissues of origin and genetic makeup display common hallmark cellular phenotypes, including sustained proliferation, suppression of cell death, and altered metabolism. These phenotypic commonalities have been proposed to stem from disruption of conserved regulatory mechanisms ...

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Nontrivial Berry phase in magnetic BaMnSb2 semimetal [Physics]

13.06.2017 | Silu Huang; Jisun Kim; W. A. Shelton; E. W. Plummer; Rongying Jin, Proceedings of the National Academy of Sciences current issue, 2017

The subject of topological materials has attracted immense attention in condensed-matter physics because they host new quantum states of matter containing Dirac, Majorana, or Weyl fermions. Although Majorana fermions can only exist on the surface of topological superconductors, Dirac and Weyl ...

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Deformable and conformal silk hydrogel inverse opal [Applied Physical Sciences]

13.06.2017 | Kyungtaek Min; Sookyoung Kim; Sunghwan Kim, Proceedings of the National Academy of Sciences current issue, 2017

Photonic crystals (PhCs) efficiently manipulate photons at the nanoscale. Applying these crystals to biological tissue that has been subjected to large deformation and humid environments can lead to fascinating bioapplications such as in vivo biosensors and artificial ocular prostheses. These ...

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Zinc-binding structure of a catalytic amyloid from solid-state NMR [Biophysics and Computational Biology]

13.06.2017 | Myungwoon Lee; Tuo Wang; Olga V. Makhlynets; Yibing Wu; Nicholas F. Polizzi; Haifan Wu; Pallavi M. Gosavi; Jan Stöhr ..., Proceedings of the National Academy of Sciences current issue, 2017

Throughout biology, amyloids are key structures in both functional proteins and the end product of pathologic protein misfolding. Amyloids might also represent an early precursor in the evolution of life because of their small molecular size and their ability to self-purify and catalyze chemical ...

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