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24.097 Aktuelle Fachpublikationen in Proceedings of the National Academy of Sciences current issue

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Plant nodulation inducers enhance horizontal gene transfer of Azorhizobium caulinodans symbiosis island [Microbiology]

29.11.2016 | Jun Ling; Hui Wang; Ping Wu; Tao Li; Yu Tang; Nawar Naseer; Huiming Zheng; Catherine Masson-Boivin; Zengtao Zhong; J ..., Proceedings of the National Academy of Sciences current issue, 2016

Horizontal gene transfer (HGT) of genomic islands is a driving force of bacterial evolution. Many pathogens and symbionts use this mechanism to spread mobile genetic elements that carry genes important for interaction with their eukaryotic hosts. However, the role of the host in this process ...

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Disparities in influenza mortality and transmission related to sociodemographic factors within Chicago in the pandemic of 1918 [Medical Sciences]

29.11.2016 | Kyra H. Grantz; Madhura S. Rane; Henrik Salje; Gregory E. Glass; Stephen E. Schachterle; Derek A. T. Cummings, Proceedings of the National Academy of Sciences current issue, 2016

Social factors have been shown to create differential burden of influenza across different geographic areas. We explored the relationship between potential aggregate-level social determinants and mortality during the 1918 influenza pandemic in Chicago using a historical dataset of 7,971 influenza ...

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Quantum entanglement of angular momentum states with quantum numbers up to 10,010 [Physics]

29.11.2016 | Robert Fickler; Geoff Campbell; Ben Buchler; Ping Koy Lam; Anton Zeilinger, Proceedings of the National Academy of Sciences current issue, 2016

Photons with a twisted phase front carry a quantized amount of orbital angular momentum (OAM) and have become important in various fields of optics, such as quantum and classical information science or optical tweezers. Because no upper limit on the OAM content per photon is known, they are also ...

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Association of PD-1/PD-L axis expression with cytolytic activity, mutational load, and prognosis in melanoma and other solid tumors [Immunology and Inflammation]

29.11.2016 | Ludmila Danilova; Hao Wang; Joel Sunshine; Genevieve J. Kaunitz; Tricia R. Cottrell; Haiying Xu; Jessica Esandrio; R ..., Proceedings of the National Academy of Sciences current issue, 2016

Programmed cell death protein-1 (PD-1)/programmed death ligand-1 (PD-L1) checkpoint blockade has led to remarkable and durable objective responses in a number of different tumor types. A better understanding of factors associated with the PD-1/PD-L axis expression is desirable, as it informs ...

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Life cycle greenhouse gas emissions and freshwater consumption associated with Bakken tight oil [Sustainability Science]

29.11.2016 | Ian J. Laurenzi; Joule A. Bergerson; Kavan Motazedi, Proceedings of the National Academy of Sciences current issue, 2016

In recent years, hydraulic fracturing and horizontal drilling have been applied to extract crude oil from tight reservoirs, including the Bakken formation. There is growing interest in understanding the greenhouse gas (GHG) emissions associated with the development of tight oil. We conducted a ...

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Role of nucleotide-binding oligomerization domain 1 (NOD1) and its variants in human cytomegalovirus control in vitro and in vivo [Microbiology]

29.11.2016 | Yi-Hsin Fan; Sujayita Roy; Rupkatha Mukhopadhyay; Arun Kapoor; Priya Duggal; Genevieve L. Wojcik; Robert F. Pass; Ra ..., Proceedings of the National Academy of Sciences current issue, 2016

Induction of nucleotide-binding oligomerization domain 2 (NOD2) and downstream receptor-interacting serine/threonine-protein kinase 2 (RIPK2) by human cytomegalovirus (HCMV) is known to up-regulate antiviral responses and suppress virus replication. We investigated the role of nucleotide-binding ...

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The emergence of longevous populations [Social Sciences]

29.11.2016 | Fernando Colchero; Roland Rau; Owen R. Jones; Julia A. Barthold; Dalia A. Conde; Adam Lenart; Laszlo Nemeth; Alexand ..., Proceedings of the National Academy of Sciences current issue, 2016

The human lifespan has traversed a long evolutionary and historical path, from short-lived primate ancestors to contemporary Japan, Sweden, and other longevity frontrunners. Analyzing this trajectory is crucial for understanding biological and sociocultural processes that determine the span of ...

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Wind speed reductions by large-scale wind turbine deployments lower turbine efficiencies and set low generation limits [Sustainability Science]

29.11.2016 | Lee M. Miller; Axel Kleidon, Proceedings of the National Academy of Sciences current issue, 2016

Wind turbines generate electricity by removing kinetic energy from the atmosphere. Large numbers of wind turbines are likely to reduce wind speeds, which lowers estimates of electricity generation from what would be presumed from unaffected conditions. Here, we test how well wind power limits ...

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Amyloid fibrils from the N-terminal prion protein fragment are infectious [Medical Sciences]

29.11.2016 | Jin-Kyu Choi; Ignazio Cali; Krystyna Surewicz; Qingzhong Kong; Pierluigi Gambetti; Witold K. Surewicz, Proceedings of the National Academy of Sciences current issue, 2016

Recombinant C-terminally truncated prion protein PrP23-144 (which corresponds to the Y145Stop PrP variant associated with a Gerstmann–Sträussler–Scheinker-like prion disease) spontaneously forms amyloid fibrils with a parallel in-register β-sheet architecture and β-sheet core mapping to residues ...

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Lifestyle chemistries from phones for individual profiling [Chemistry]

29.11.2016 | Amina Bouslimani; Alexey V. Melnik; Zhenjiang Xu; Amnon Amir; Ricardo R. da Silva; Mingxun Wang; Nuno Bandeira; Theo ..., Proceedings of the National Academy of Sciences current issue, 2016

Imagine a scenario where personal belongings such as pens, keys, phones, or handbags are found at an investigative site. It is often valuable to the investigative team that is trying to trace back the belongings to an individual to understand their personal habits, even when DNA evidence is also ...

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