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506.100 Aktuelle Fachpublikationen zum Thema temperature

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Metformin and respiratory chain complex I: the last piece of the puzzle?

01.11.2014 | Fontaine E, Biochemical Journal, 2014

Metformin is the most widely prescribed drug used to treat patients affected by Type2 diabetes. Metformin has also been shown to prevent some forms of cell death; however, evidence suggests that it may have anti-neoplastic properties. All of these effects have been attributed to complex I ...


NTBI unveiled by chelatable fluorescent beads

01.11.2014 | Sebastiani G; Pantopoulos K, Biochemical Journal, 2014

Non-transferrin-bound iron (NTBI) emerges in plasma of patients with systemic iron overload, but has also been documented in further pathological conditions. Quantification of NTBI can be useful for diagnosis and management of these disorders. However, currently available detection methods are ...


Dual-view plane illumination microscopy for rapid and spatially isotropic imaging

01.11.2014 | Abhishek Kumar; Yicong Wu; Ryan Christensen; Panagiotis Chandris; William Gandler; Evan McCreedy; Alexandra Bokinsky ..., Nature Protocols, 2014

Nature Protocols 9, 2555 (2014). doi:10.1038/nprot.2014.172 Authors: Abhishek Kumar, Yicong Wu, Ryan Christensen, Panagiotis Chandris, William Gandler, Evan McCreedy, Alexandra Bokinsky, Daniel A Colón-Ramos, Zhirong Bao, Matthew McAuliffe, Gary Rondeau & Hari Shroff We ...


Fe(Me2-bpy)2(NCSe)2 spin-crossover micro- and nanoparticles showing a spin-state switching above 250 K.

15.10.2014 | Luong Lam Nguyen; Regis Guillot; Jerome Laisney; Lionel Rechignat; Salma Bedoui; Gábor Molnár; Eric RIVIERE; Marie-L ..., New Journal of Chemistry, 2014

We present the study of nano- and microparticles of the Fe(Me2-bpy)2(NCSe)2 spin-crossover complex prepared from the diamagnetic precursor [Fe(Me2-bpy)3](NCSe)2.S. Two solvates of the latter were characterized by single-crystal X-ray structures at 100 K (S = 2MeOH or 3H2O). The extraction of one ...


Temperature and oxygen-concentration dependence of singlet oxygen production by RuPhen as induced by quasi-continuous excitation

15.10.2014 | Jaroslav Varchola; Veronika Huntosova; Daniel Jancura; Georges Wagnieres; Pavol Miskovsky; Gregor Bano, Photochemical & Photobiological Sciences, 2014

Assessment of oxygen partial pressure (pO2) by luminescence lifetime measurements of ruthenium coordination complexes has been studied intensively during the last decades. RuPhen (dichlorotris(1,10-phenanthroline) ruthenium(II) hydrate) is a water soluble molecule that has been tested previously ...


Elemental and molecular mass spectrometry for integrated selenosugar speciation in liver and kidney tissues of maternal feeding and supplemented rats

15.10.2014 | Hector Gonzalez Iglesias; M. Luisa Fernandez; Ying Lu; Sonia Fernández Menéndez; Spiros A Pergantis; Alfredo Sanz-Medel, Journal of Analytical Atomic Spectrometry, 2014

The development of methods assessing the nutritional value and metabolism of selenium are of growing interest. In this work, the integrated used of a methodology based on HPLC- isotope pattern deconvolution (IPD)-ICP-MS and a molecular tandem mass spectrometric technique such as HPLC-APCI-MS/MS, ...


The spatial-temporal characteristics of type I collagen-based extracellular matrix

15.10.2014 | Christopher Allen Rucksack Jones; Long Liang; Daniel Lin; Yang Jiao; Bo Sun, Soft Matter, 2014

Type I collagen abounds in mammalian extracellular matrix (ECM) and is crucial to many biophysical processes. While previous studies have mostly focused on bulk averaged properties, here we provide a comprehensive and quantitative spatial-temporal characterization of the microstructure of type I ...


3D hierarchical ZnOHF nanostructures: synthesis, characterization and photocatalytic properties

15.10.2014 | Miao Wang; Tongming Sun; Yujun Shi; Guoqing Jiang; Yanfeng Tang, CrystEngComm, 2014

Abstract: 3D hierarchical ZnOHF nanoflowers with mean diameter of 200 nm have been synthesized via a simple template-free hydrothermal route by using (NH4)2SiF6 as the fluoride source. The crystalline phase and morphologies of the as-prepared products have been characterized by XRD, SEM and TEM. ...


Mechanistic studies on the indole prenyltransferases

15.10.2014 | Martin E. Tanner, Natural Product Reports, 2014

Covering: up to 2014Prenylated indole alkaloids comprise a large and structurally diverse family of natural products that often display potent biological activities. In recent years a large family of prenyltransferases that install prenyl groups onto the indole core have been discovered. While ...


Design and synthesis of a new dimeric xanthone derivative: enhancement of G-quadruplex selectivity and telomere damage

15.10.2014 | Marco Franceschin; Daniele Nocioni; Annamaria Biroccio; Chiara Cingolani; Emanuela Micheli; Stefano Cacchione; Aless ..., Organic & Biomolecular Chemistry, 2014

Following the results we previously reported on a series of xanthene and xanthone derivatives as G-quadruplex stabilizing ligands, in order to obtain a more selective compound with respect to the previous generation of derivatives, we decided to modify the structure of the core ligand, ...


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