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1.042 Aktuelle Fachpublikationen zum Thema temperature

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Evaluation of the Role of G Protein-Coupled Receptor Kinase 3 in Desensitization of Mouse Odorant Receptors in a Mammalian Cell Line and in Olfactory Sensory Neurons

01.11.2014 | Aya Kato; Johannes Reisert; Sayoko Ihara; Keiichi Yoshikawa; Kazushige Touhara, Chemical Senses, 2014

Thousands of odors are sensed and discriminated by G protein-coupled odorant receptors (ORs) expressed in olfactory sensory neurons (OSNs). G protein-coupled receptor kinases (GRKs) may have a role in desensitization of ORs. However, whether ORs are susceptible to agonist-dependent ...


Evidence that Humans Can Taste Glucose Polymers

01.11.2014 | Trina J. Lapis; Michael H. Penner; Juyun Lim, Chemical Senses, 2014

The sense of taste is essential for identifying potential nutrients and poisons. Accordingly, specialized taste receptor cells are activated by food-derived chemicals. Because of its importance in the human diet, oral detection of starch, or its degradation products, would presumably be highly ...


Using Sniffing Behavior to Differentiate True Negative from False Negative Responses in Trained Scent-Detection Dogs

01.11.2014 | Astrid Concha; Daniel S. Mills; Alexandre Feugier; Helen Zulch; Claire Guest; Rob Harris; Thomas W. Pike, Chemical Senses, 2014

False negatives are recorded in every chemical detection system, but when animals are used as a scent detector, some false negatives can arise as a result of a failure in the link between detection and the trained alert response, or a failure of the handler to identify the positive alert. A false ...


A Determinant of Odorant Specificity Is Located at the Extracellular Loop 2-Transmembrane Domain 4 Interface of an Anopheles gambiae Odorant Receptor Subunit

01.11.2014 | David T. Hughes; Guirong Wang; Laurence J. Zwiebel; Charles W. Luetje, Chemical Senses, 2014

To explore the structural basis for odorant specificity in odorant receptors of the human malaria vector mosquito, Anopheles gambiae, odorant-binding subunits (Agam\Ors) expressed in Xenopus oocytes in combination with Agam\Orco (coreceptor subunit) were assayed by 2-electrode voltage clamp ...


Gray Matter Volume Reduction of Olfactory Cortices in Patients With Idiopathic Olfactory Loss

01.11.2014 | Linyin Yao; Jayant Marian Pinto; Xiaoli Yi; Li Li; Peng Peng; Yongxiang Wei, Chemical Senses, 2014

Idiopathic olfactory loss (IOL) is a common olfactory disorder. Little is known about the pathophysiology of this disease. Previous studies demonstrated decreased olfactory bulb (OB) volume in IOL patients when compared with controls. The aim of our study was to investigate structural brain ...


Sodium Aspartate as a Specific Enhancer of Salty Taste Perception—Sodium Aspartate Is a Possible Candidate to Decrease Excessive Intake of Dietary Salt

01.11.2014 | Tomohiro Nakagawa; Jun Kohori; Shin Koike; Yoshihisa Katsuragi; Takayuki Shoji, Chemical Senses, 2014

The excessive intake of dietary salt is a global issue in health. Attempts have been made to address this issue, including the development of salt substitutes. Yet, none of these substances are currently in wide use, because of their weak saltiness. The purpose of this study was to assess the ...


Responsiveness of Human Neonates to the Odor of 5{alpha}-Androst-16-en-3-one: A Behavioral Paradox?

01.10.2014 | Helene M. Loos; Sébastien Doucet; Robert Soussignan; Constanze Hartmann; Karine Durand; Ralf Dittrich; Paul Sagot; A ..., Chemical Senses, 2014

The odorous steroid 5α-androst-16-en-3-one (AND) occurs in numerous biological fluids in mammals, including man, where it is believed to play a chemocommunicative role. As AND was recently detected in milk and amniotic fluid, sensitivity and hedonic responses to this substance were assessed in ...


Endoscopic, Radiological, and Symptom Correlation of Olfactory Dysfunction in Pre- and Postsurgical Patients of Chronic Rhinosinusitis

01.10.2014 | Divya Gupta; Achal Gulati; Ishwar Singh; Uma Tekur, Chemical Senses, 2014

The aim of the present study was to correlate olfactory dysfunction determined with psychophysical testing with nasal endoscopy, computed tomography (CT) scan, and patient’s self-assessed olfactory deficit in patients of chronic rhinosinusitis (CRS) before and after sinus surgery. It was a ...


Differences in BOLD Responses to Intragastrically Infused Glucose and Saccharin in Rats

01.10.2014 | Tomokazu Tsurugizawa; Hisayuki Uneyama, Chemical Senses, 2014

The postingestive effect is different between caloric and noncaloric sweeteners. The gut administration of glucose induces a preference for flavored water which is paired with the intragastric infusion of glucose. However, a comparison of the brain response to the gut glucose and saccharin ...


Physiological Organization and Topographic Mapping of the Antennal Olfactory Sensory Neurons in Female Hawkmoths, Manduca sexta

01.10.2014 | Majid Ghaninia; Shannon B. Olsson; Bill S. Hansson, Chemical Senses, 2014

The hawkmoth, Manduca sexta, has been a keystone system for developmental, neurobiological, and ecological studies for several decades. Because many of its behaviors are driven by olfactory cues, a thorough understanding of the Manduca olfactory system is essential to studying its biology. With ...


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