Amoxapine
Amoxapine (brand-names Asendin®, Asendis®, Defanyl®, Demolox®, Moxadil®) is a tricyclic antidepressant of the dibenzoxazepine class. It is used in the treatment of depression, panic disorders and bipolar disorder.
Amoxapine is a strong reuptake inhibitor of norepinephrine and weak reuptake inhibitor of serotonin. One of its major metabolites, 7-hydroxyamoxapine, has a dopamine receptor blocking effect.
See also
References
- Mosby Year-Book, Inc. (1995). Physician's GenRx: The Complete Drug Reference (5th Ed.). Riverside, CT: Denniston Publishing Co.
- Palfai, T. & Jankiewicz, H. (1997). Drugs and Human Behavior (2nd Ed.). Madison, WI: Brown & Benchmark.
- Hedges, D. & Burchfield, C. (2006). Mind, Brain, and Drug: An Introduction to Psychopharmacology. Boston, MA: Pearson.
| Psychoanaleptics: antidepressants (N06A) |
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| MAOIs | Iproclozide • Iproniazid • Isocarboxazid • Nialamide • Pargyline • Phenelzine • Rasagiline • Selegiline • Toloxatone • Tranylcypromine
RIMAs: Brofaromine • Beta-carbolines (Harmaline) • Moclobemide |
|---|
| RIs |
| S RI |
SS RI (Alaproclate, Citalopram, Dapoxetine, Escitalopram, Etoperidone, Fluoxetine, Fluvoxamine, Paroxetine, Sertraline, Zimelidine)
• TCAs/Tetras (Clomipramine, Nefazodone, Trazodone) |
| N RI / A RI |
Atomoxetine • Maprotiline • Reboxetine • Viloxazine • TCAs/Tetras (Amitriptyline, Amoxapine, Butriptyline, Desipramine/Lofepramine, Dibenzepin, Dothiepin, Doxepin, Imipramine, Iprindole, Melitracen, Nortriptyline, Opipramol, Protriptyline, Trimipramine, Maprotiline) |
| D RI |
Vanoxerine • Phenmetrazine • TCAs (Amineptine) |
| SN RI |
Bicifadine • Desvenlafaxine • Duloxetine • Milnacipran • Nefazodone • Venlafaxine |
| ND RI |
Bupropion |
| SND RI |
Brasofensine • Tesofensine • Nomifensine |
|
|---|
| SSREs | Tianeptine |
|---|
| AAs | Tetras (Mianserin, Mirtazapine) |
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