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Beraprost
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Please help improve this article by adding reliable references. Unsourced material may be challenged and removed. (June 2007) |
Beraprost is a synthetic analogue of prostacyclin, under clinical trials for the treatment of pulmonary hypertension. It is also being studied for use in avoiding reperfusion injury.
Clinical pharmacology
As an analogue of prostacyclin PGI2, beraprost effects vasodilation, which in turn lowers the blood pressure. Beraprost also inhibits platelet aggregation, though the role this phenomenon may play in relation to pulmonary hypertension has yet to be determined.
Dosage and administration
Beraprost is administered orally as a pill.
| Antithrombotics (thrombolytics, anticoagulants and antiplatelet drugs) (B01) |
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| Vitamin K antagonists | Acenocoumarol • Clorindione • Coumatetralyl • Dicumarol (Dicoumarol) • Diphenadione • Ethyl biscoumacetate • Phenprocoumon • Phenindione • Tioclomarol • Warfarin |
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| Heparin group | Antithrombin III • Danaparoid • Heparin • Sulodexide • low molecular weight heparin (Bemiparin, Dalteparin, Enoxaparin, Nadroparin, Parnaparin, Reviparin, Tinzaparin) |
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| Glycoprotein IIb/IIIa inhibitors | Abciximab • Eptifibatide • Tirofiban |
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Other platelet
aggregation inhibitors | Acetylsalicylic acid/Aspirin • Aloxiprin • Ditazole • Carbasalate calcium • Cloricromen • Dipyridamole • Indobufen • Picotamide • Triflusal • ADP receptor inhibitors (Clopidogrel, Ticlopidine, Prasugrel) • prostaglandin analogue (Beraprost, Prostacyclin, Iloprost, Treprostinil) |
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| Enzymes | plasminogen activators (Alteplase/Reteplase/Tenecteplase, Streptokinase, Urokinase/Saruplase, Anistreplase) • other serine endopeptidases (Ancrod, Drotrecogin alfa/Protein C, Fibrinolysin) • Brinase |
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| Direct thrombin inhibitors | Argatroban • Bivalirudin • Dabigatran • Desirudin • Hirudin • Lepirudin • Melagatran • Ximelagatran |
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| Other antithrombotics | Defibrotide • Dermatan sulfate • Fondaparinux • Rivaroxaban |
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| Non-medicinal | Citrate • EDTA • Oxalate |
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| Medications used in the management of pulmonary arterial hypertension (B01, C02) |
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| Prostacyclin analogues | Beraprost, Epoprostenol, Iloprost, Treprostinil |
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| Endothelin receptor antagonists | Ambrisentan, Bosentan, Sitaxsentan |
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| PDE5 inhibitors | Sildenafil, Tadalafil |
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| Adjunctive therapy | Calcium channel blockers, Diuretics, Digoxin, Oxygen therapy, Warfarin |
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Beraprost". A list of authors is available in Wikipedia.
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