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Phenformin
Phenformin is an anti-diabetic drug from the biguanide class. It is no longer widely available because it is known to induce lactic acidosis.[1]
Like metformin, phenformin leads to weight loss, something often desirable in type 2 diabetics, and it is for this reason that there is still some interest in it.[2]
References
- ^ Enia G, Garozzo M, Zoccali C (1997). "Lactic acidosis induced by phenformin is still a public health problem in Italy.". BMJ 315 (7120): 1466-7. PMID 9418116.
- ^ Rosand J, Friedberg J, Yang J (1997). "Fatal phenformin-associated lactic acidosis.". Ann Intern Med 127 (2): 170. PMID 9230023.
| Oral antidiabetic drugs and Insulin analogs (A10) |
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| Biguanides | Metformin |
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| Sulfonylureas | Chlorpropamide, Glibenclamide (Glyburide), Gliclazide, Glimepiride, Glipizide, Gliquidone, Tolazamide, Tolbutamide |
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| Alpha-glucosidase inhibitors | Acarbose, Miglitol, Voglibose |
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| Thiazolidinediones (TZD) | Pioglitazone, Rosiglitazone, Troglitazone |
|---|
| Meglitinides | Nateglinide, Repaglinide, Mitiglinide |
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| Dipeptidyl peptidase-4 (DPP-4) inhibitors | Saxagliptin, Sitagliptin, Vildagliptin |
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| Glucagon-like peptide-1 analog | Exenatide |
|---|
| Insulin analogs | fast acting (Insulin lispro, Insulin aspart, Insulin glulisine), intermediate-acting (NPH insulin), long acting (Insulin glargine, Insulin detemir) |
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Phenformin". A list of authors is available in Wikipedia.
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