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Prostaglandin analogue
Synthetic prostaglandin analogues are molecules which are manufactured to bind to a prostaglandin receptor.
Wider use of prostaglandin analogues is limited by unwanted side effects and their abortive potential.
Uses
- Prostaglandin analogues such as misoprostol are used in treatment of duodenal and gastric ulcers. They exert antisecretory and cytoprotective properties and are especially indicated for the elderly on continuous doses of NSAIDs.
- Prostaglandin analogues can also be used in the management of open-angle glaucoma. They reduce intra-ocular pressure by enhancing uveoscleral outflow and may also have some effect on the trabecular meshwork as well. Latanoprost, travoprost, unoprostone and bimatoprost are examples of prostaglandin analogues used in the management of open-angle glaucoma.
| Drugs for acid related disorders: Drugs for peptic ulcer and GERD/GORD (A02B) |
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| H₂-receptor antagonists | Cimetidine, Famotidine, Nizatidine, Ranitidine, Roxatidine |
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| Prostaglandins/analogues | Misoprostol, Enprostil |
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| Proton pump inhibitors | Esomeprazole, Lansoprazole, Omeprazole, Pantoprazole, Rabeprazole, Tenatoprazole |
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| Other | Carbenoxolone, Sucralfate, Pirenzepine |
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| Antithrombotics (thrombolytics, anticoagulants and antiplatelet drugs) (B01) |
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| Vitamin K antagonists | Acenocoumarol • Clorindione • Coumatetralyl • Dicumarol (Dicoumarol) • Diphenadione • Ethyl biscoumacetate • Phenprocoumon • Phenindione • Tioclomarol • Warfarin |
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| Heparin group | Antithrombin III • Danaparoid • Heparin • Sulodexide • low molecular weight heparin (Bemiparin, Dalteparin, Enoxaparin, Nadroparin, Parnaparin, Reviparin, Tinzaparin) |
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| Glycoprotein IIb/IIIa inhibitors | Abciximab • Eptifibatide • Tirofiban |
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Other platelet
aggregation inhibitors | Acetylsalicylic acid/Aspirin • Aloxiprin • Ditazole • Carbasalate calcium • Cloricromen • Dipyridamole • Indobufen • Picotamide • Triflusal • ADP receptor inhibitors (Clopidogrel, Ticlopidine, Prasugrel) • prostaglandin analogue (Beraprost, Prostacyclin, Iloprost, Treprostinil) |
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| Enzymes | plasminogen activators (Alteplase/Reteplase/Tenecteplase, Streptokinase, Urokinase/Saruplase, Anistreplase) • other serine endopeptidases (Ancrod, Drotrecogin alfa/Protein C, Fibrinolysin) • Brinase |
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| Direct thrombin inhibitors | Argatroban • Bivalirudin • Dabigatran • Desirudin • Hirudin • Lepirudin • Melagatran • Ximelagatran |
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| Other antithrombotics | Defibrotide • Dermatan sulfate • Fondaparinux • Rivaroxaban |
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| Non-medicinal | Citrate • EDTA • Oxalate |
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Prostaglandin_analogue". A list of authors is available in Wikipedia.
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