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A light-up fluorescence assay for tumor cell detection based on bifunctional split aptamers

The light-up aptamers have attracted growing attention due to their advantages of label-free and low fluorescence background. In this work, we developed a light-up fluorescence assay for label-free detection of tumor cells based on the bifunctional split aptamer (BFSA) which contained two DNA strands (BFSA-a

Autoren:   Yuqiong Sun; Baoyin Yuan; Meitao Deng; Qing Wang; Jin Huang; Qiuping Guo; Jianbo Liu; Xiaohai Yang; Kemin Wang
Journal:   Analyst
DOI:   10.1039/C8AN01008K
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