21.01.2016 | Wanklyn, Ceri; Burton, Dan; Enston, Emma; Bartlett, Carrie-Ann; Taylor, Sarah; Raniczkowska, Aleksandra; Black, Murd ..., Chemistry Central Journal , 2016

Background: Cannabis has an adverse effect on the ability to drive safely, therefore a rapid disposable test for Δ 9 -tetrahydrocannabinol (Δ 9 -THC), the psychoactive component of cannabis, is highly desirable for ...

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29.12.2015 | El-Asmy, Ahmed; Jeragh, Bakir; Ali, Mayada, Chemistry Central Journal , 2015

Background: Hydrazones and their metal complexes were heavily studied due to their pharmacological applications such as antimicrobial, anticonvulsant analgesic, anti-inflammatory and anti-cancer agents. This work aims to synthesize and characterize novel complexes of VO ...

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24.12.2015 | Lv, Xinmiao; Zhao, Siyu; Ning, Zhangchi; Zeng, Honglian; Shu, Yisong; Tao, Ou; Xiao, Cheng; Lu, Cheng; Liu, Yuanyan, Chemistry Central Journal , 2015

Citrus fruits, which are cultivated worldwide, have been recognized as some of the most high-consumption fruits in terms of energy, nutrients and health supplements. What is more, a number of these fruits have been used as traditional medicinal herbs to cure diseases in several Asian ...

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09.12.2015 | Dibrivnyi, Volodymyr; Sobechko, Iryna; Puniak, Marian; Horak, Yuriy; Obushak, Mykola; Van-Chin-Syan, Yuriy; Andriy, ..., Chemistry Central Journal , 2015

Background: The aim of the current work was to determine thermo dynamical properties of 5(2-nitro phenyl)-furan-2-carbaldehyde, 5(3-nitro phenyl)-furan-2-carbaldehyde and 5(4-nitro phenyl)-furan-2-carbaldehyde. Results: The temperature dependence of saturated vapor pressure of 5(2-nitro ...

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09.12.2015 | Chen, Yujie; Xu, Liang; Zhao, Yuancen; Zhao, Zhongzhen; Chen, Hubiao; Yi, Tao; Qin, Minjian; Liang, Zhitao, Chemistry Central Journal , 2015

Background: The root of Panax quinquefolium L., famous as American ginseng all over the world, is one of the most widely-used medicinal or edible materials. Ginsenosides are recognized as the main bioactive chemical components responsible for various functions of American ginseng. In this study, ...

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26.11.2015 | Chen, Xi; Barclay, Jeff W; Burgoyne, Robert D; Morgan, Alan, Chemistry Central Journal , 2015

Age-associated neurodegenerative disorders such as Alzheimer’s disease are a major public health challenge, due to the demographic increase in the proportion of older individuals in society. However, the relatively few currently approved drugs for these conditions provide only symptomatic relief. ...

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25.11.2015 | Morosanova, Maria A; Morosanova, Elena I, Chemistry Central Journal , 2015

Background: Salicylic acid and its derivatives are widely used drugs with potential toxicity. The main areas of salicylate derivatives determination are biological liquids and pharmaceuticals analysis. Results: Silica-titania xerogel has been used for solid phase spectrophotometric determination ...

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21.11.2015 | Kurdyumov, Alexey S; Manuvera, Valentin A; Baskova, Isolda P; Lazarev, Vassili N, BMC Biochemistry, 2015

Background: Destabilase-Lysozyme (mlDL) is a multifunctional i-type enzyme that has been found in the secretions from the salivary glands of medicinal leeches. mlDL has been shown to exhibit isopeptidase, muramidase and antibacterial activity. This enzyme attracts interest because it expresses ...

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17.11.2015 | Barakat, Assem; Al-Majid, Abdullah M; Lotfy, Gehad; Arshad, Fiza; Yousuf, Sammer; Choudhary, M. I; Ashraf, Sajda; Ul ..., Chemistry Central Journal , 2015

Background: Discovery of potent inhibitors of urease (jack bean) enzyme is the first step in the development of drugs against diseases caused by ureolytic enzyme. Results: Thirty-two derivatives of barbituric acid as zwitterionic adducts of diethyl ammonium salts were synthesized. All synthesized ...

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11.11.2015 | Morrill, Johan; Kulcinskaja, Evelina; Sulewska, Anna M; Lahtinen, Sampo; Stålbrand, Henrik; Svensson, Birte; Abou Ha ..., BMC Biochemistry, 2015

Background: β-Mannans are abundant and diverse plant structural and storage polysaccharides. Certain human gut microbiota members including health-promoting Bifidobacterium spp. catabolize dietary mannans. Little insight is available on the enzymology of mannan deconstruction in the gut ...

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