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451 Aktuelle Fachpublikationen von BioMed Central

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A novel immunoglobulin G monolayer silver bio-nanocomposite

06.10.2015 | Matea, Cristian T; Mocan, Teodora; Zaharie, Florin; Iancu, Cornel; Mocan, Lucian, Chemistry Central Journal , 2015

Background: Nanoparticles have a large number of surface atoms, which translates into a significant increase in the surface energy. Once introduced in a biological environment they tend to interact with proteins and form a protein corona shell. The aim of this study was to develop a novel, ...

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Application of α-aminoisobutyric acid and β-aminoisobutyric acid inhibits pericarp browning of harvested longan fruit

06.10.2015 | Wang, Hui; Zhi, Wei; Qu, Hongxia; Lin, Hetong; Jiang, Yueming, Chemistry Central Journal , 2015

Background: Pericarp browning is a critical problem resulting in reduced commercial value and shelf life of longan fruit. Results: Two non-protein amino acids, α-aminoisobutyric acid (AIB) and β-aminoisobutyric acid (BAIB) at 100 and 1mM were applied to longan fruit prior to storage for up to ...

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Phytochemical composition, antiparasitic and α–glucosidase inhibition activities from Pelliciera rhizophorae

28.09.2015 | López, Dioxelis; Cherigo, Lilia; Spadafora, Carmenza; Loza-Mejía, Marco A; Martínez-Luis, Sergio, Chemistry Central Journal , 2015

Background: Panama has an extensive mangrove area and it is one of the countries with the highest biodiversity in America. Mangroves are widely used in traditional medicine, nevertheless, there are very few studies that validates their medicinal properties in America. Given the urgent need for ...

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Diagnostic techniques in deflagration and detonation studies

28.09.2015 | Proud, William G; Williamson, David M; Field, John E; Walley, Stephen M, Chemistry Central Journal , 2015

Advances in experimental, high-speed techniques can be used to explore the processes occurring within energetic materials. This review describes techniques used to study a wide range of processes: hot-spot formation, ignition thresholds, deflagration, sensitivity and finally the detonation ...

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Prediction of 1-octanol solubilities using data from the Open Notebook Science Challenge

24.09.2015 | Buonaiuto, Michael A; Lang, Andrew SID, Chemistry Central Journal , 2015

Background: 1-Octanol solubility is important in a variety of applications involving pharmacology and environmental chemistry. Current models are linear in nature and often require foreknowledge of either melting point or aqueous solubility. Here we extend the range of applicability of 1-octanol ...

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Synthesis and antibacterial activity of novel 5,6,7,8-tetrahydroimidazo[1,2-a]pyrimidine-2-carbohydrazide derivatives

24.09.2015 | Kethireddy, Shashikala; Eppakayala, Laxminarayana; Maringanti, Thirumala C, Chemistry Central Journal , 2015

Background: The intensely increasing multi-drug resistant microbial infections have encouraged the search for new antimicrobial agents. Hydrazone derivatives are known to exhibit a wide variety of biological activities including anti-microbial. In heterocyclic moiety, imidazo[1,2-a]pyrimidines ...

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Dial-a-molecule workshop: computational prediction of reaction outcomes and optimum synthetic routes

23.09.2015 | Kilpin, Kelly J; Goodman, Jonathan M; Johnson, A. P; Whitby, Richard J, Chemistry Central Journal , 2015

Computational prediction of reaction outcomes and optimum synthetic routes was a two-day meeting and workshop organised by the EPSRC Dial-a-molecule grand challenge network. Forty delegates discussed computer predictions of synthetic routes and reactions, and considered their relevance to ...

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Growth of bubbles in liquid

21.09.2015 | Smirnov, Boris M; Berry, R. S, Chemistry Central Journal , 2015

Background: Evolution of a gas injected in a liquid is analyzed using the example of the behavior of oxygen molecules in water in which bubbles of gas molecules grow slowly by attachment of gas molecules to bubbles, the bubbles then associate and finally flow up to the liquid–gas interface and ...

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Sandal reactive dyes decolorization and cytotoxicity reduction using manganese peroxidase immobilized onto polyvinyl alcohol-alginate beads

15.09.2015 | Bilal, Muhammad; Asgher, Muhammad, Chemistry Central Journal , 2015

Background: Fungal manganese peroxidases (MnPs) have great potential as bio-remediating agents and can be used continuously in the immobilized form like many other enzymes. Results: In the present study, purified manganese peroxidase (MnP) enzyme isolated from Ganoderma lucidum IBL-05 was ...

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Respiration and substrate transport rates as well as reactive oxygen species production distinguish mitochondria from brain and liver

10.09.2015 | Gusdon, Aaron M; Fernandez-Bueno, Gabriel A; Wohlgemuth, Stephanie; Fernandez, Jenelle; Chen, Jing; Mathews, Clayton E, BMC Biochemistry, 2015

Background: Aberrant mitochondrial function, including excessive reactive oxygen species (ROS) production, has been implicated in the pathogenesis of human diseases. The use of mitochondrial inhibitors to ascertain the sites in the electron transport chain (ETC) resulting in altered ROS ...

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