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10.005 Aktuelle Fachpublikationen von Nature Publishing Group

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Cancer immunotherapy making headway

23.05.2018 | Amos Matsiko, Nature Materials, 2018

Cancer immunotherapy making headway Cancer immunotherapy making headway, Published online: 23 May 2018; doi:10.1038/s41563-018-0091-8 Cancer immunotherapy making headway

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Dipeptidyl peptidase IV (DPP-4) inhibition alleviates pulmonary arterial remodeling in experimental pulmonary hypertension

22.05.2018 | Jian Xu; Jingjing Wang; Mengyu He; Honghao Han; Weiping Xie; Hong Wang; Hui Kong, Laboratory Investigation, 2018

Dipeptidyl peptidase IV (DPP-4) is well known for its role in glucose homeostasis, and DPP-4 inhibitor (DPP-4i) exhibits multiple actionsin cardiovascular diseases. However, the effect of DPP-4i on pulmonary hypertension (PH) remains unclear. Therefore, this study aims to investigate the effect ...

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S100A4 protects mice from high-fat diet-induced obesity and inflammation

22.05.2018 | Shasha Hou; Ying Jiao; Qi Yuan; Junfeng Zhai; Tian Tian; Kaiji Sun; Zhinan Chen; Zhenlong Wu; Jinhua Zhang, Laboratory Investigation, 2018

As a member from S100 calcium-binding protein family, S100A4 is ubiquitous and elevated in tumor progression and metastasis, but its role in regulating obesity has not been well characterized. In this study, we showed that S100A4 was mainly expressed by stromal cells in adipose tissue and the ...

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Publisher Correction: Spatiotemporal control of laser intensity

22.05.2018 | Dustin H. Froula; David Turnbull; Andrew S. Davies; Terrance J. Kessler; Dan Haberberger; John P. Palastro; Seung-Wh ..., Nature Photonics, 2018

Publisher Correction: Spatiotemporal control of laser intensity Publisher Correction: Spatiotemporal control of laser intensity, Published online: 22 May 2018; doi:10.1038/s41566-018-0192-6 Publisher Correction: Spatiotemporal control of laser intensity

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Publisher Correction: Quantum engineering of transistors based on 2D materials heterostructures

22.05.2018 | Giuseppe Iannaccone; Francesco Bonaccorso; Luigi Colombo; Gianluca Fiori, Nature Nanotechnology, 2018

Publisher Correction: Quantum engineering of transistors based on 2D materials heterostructures Publisher Correction: Quantum engineering of transistors based on 2D materials heterostructures, Published online: 22 May 2018; doi:10.1038/s41565-018-0136-9 Publisher Correction: Quantum engineering ...

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BMP-2 restoration aids in recovery from liver fibrosis by attenuating TGF-β1 signaling

22.05.2018 | Yueh-Hua Chung; Ying-Hsien Huang; Tien-Huei Chu; Chun-Lin Chen; Pey-Ru Lin; Shih-Chung Huang; Deng-Chyang Wu; Chao-C ..., Laboratory Investigation, 2018

Transforming growth factor-β (TGF-β) plays a central role in hepatic fibrogenesis. This study investigated the function and mechanism of bone morphogenetic protein-2 (BMP-2) in regulation of hepatic fibrogenesis. BMP-2 expression in fibrotic liver was measured in human tissue microarray and mouse ...

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A hot debut

21.05.2018 | Joseph N. Talmadge, Nature Physics, 2018

A hot debut A hot debut, Published online: 21 May 2018; doi:10.1038/s41567-018-0158-0 The first campaign of the largest stellarator ever built, Wendelstein 7-X, has been successful, achieving high electron temperatures and minimal self-generated plasma current. This is very encouraging for ...

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Automated, parallel mass spectrometry imaging and structural identification of lipids

21.05.2018 | Shane R. Ellis; Martin R. L. Paine; Gert B. Eijkel; Josch K. Pauling; Peter Husen; Mark W. Jervelund; Martin Hermans ..., Nature Methods, 2018

Automated, parallel mass spectrometry imaging and structural identification of lipids Automated, parallel mass spectrometry imaging and structural identification of lipids, Published online: 21 May 2018; doi:10.1038/s41592-018-0010-6 An automated method coupling tandem mass spectrometry with ...

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Gate-tunable third-order nonlinear optical response of massless Dirac fermions in graphene

21.05.2018 | Tao Jiang; Di Huang; Jinluo Cheng; Xiaodong Fan; Zhihong Zhang; Yuwei Shan; Yangfan Yi; Yunyun Dai; Lei Shi; Kaihui ..., Nature Photonics, 2018

Graphene with massless Dirac fermions can have exceptionally strong third-order optical nonlinearities. Yet reported values of nonlinear optical susceptibilities for third-harmonic generation (THG), four-wave mixing (FWM) and self-phase modulation vary over six orders of magnitude. Such variation ...

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Magnetic configuration effects on the Wendelstein 7-X stellarator

21.05.2018 | A. Dinklage; C. D. Beidler; P. Helander; G. Fuchert; H. Maaßberg; K. Rahbarnia; T. Sunn Pedersen; Y. Turkin; R. ..., Nature Physics, 2018

The two leading concepts for confining high-temperature fusion plasmas are the tokamak and the stellarator. Tokamaks are rotationally symmetric and use a large plasma current to achieve confinement, whereas stellarators are non-axisymmetric and employ three-dimensionally shaped magnetic field ...

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