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3.484 Aktuelle Fachpublikationen in European Journal of Medicinal Chemistry

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Therapeutic journery of nitrogen mustard as alkylating anticancer agents: Historic to future perspectives

15.04.2018 | Author(s): Rajesh K. Singh, Sahil Kumar, D.N. Prasad, T.R. Bhardwaj, European Journal of Medicinal Chemistry, 2018

Publication date: 10 May 2018 Source:European Journal of Medicinal Chemistry, Volume 151 Author(s): Rajesh K. Singh, Sahil Kumar, D.N. Prasad, T.R. Bhardwaj Cancer is considered as one of the most serious health problems today. The discovery of nitrogen mustard as an alkylating ...

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Photoinduced anticancer activity studies of iridium(III) complexes targeting mitochondria and tubules

15.04.2018 | Author(s): Wen-Yao Zhang, Qian-Yan Yi, Yang-Jie Wang, Fan Du, Miao He, Bing Tang, Dan Wan, Yun-Jun L ..., European Journal of Medicinal Chemistry, 2018

Publication date: 10 May 2018 Source:European Journal of Medicinal Chemistry, Volume 151 Author(s): Wen-Yao Zhang, Qian-Yan Yi, Yang-Jie Wang, Fan Du, Miao He, Bing Tang, Dan Wan, Yun-Jun Liu, Hong-Liang Huang Three new iridium (III) complexes [Ir (ppy)2 (ipbc)](PF6) (1), ...

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Investigating isoindoline, tetrahydroisoquinoline, and tetrahydrobenzazepine scaffolds for their sigma receptor binding properties

15.04.2018 | Author(s): Kathryn Linkens, Hayden R. Schmidt, James J. Sahn, Andrew C. Kruse, Stephen F. Martin, European Journal of Medicinal Chemistry, 2018

Publication date: 10 May 2018 Source:European Journal of Medicinal Chemistry, Volume 151 Author(s): Kathryn Linkens, Hayden R. Schmidt, James J. Sahn, Andrew C. Kruse, Stephen F. Martin Substituted norbenzomorphans are known to display high affinity and selectivity for the two ...

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Design, synthesis and activity of BBI608 derivatives targeting on stem cells

15.04.2018 | Author(s): Qifan Zhou, Chen Peng, Fangyu Du, Linbo Zhou, Yajie Shi, Yang Du, Dongdong Liu, Wenjiao S ..., European Journal of Medicinal Chemistry, 2018

Publication date: 10 May 2018 Source:European Journal of Medicinal Chemistry, Volume 151 Author(s): Qifan Zhou, Chen Peng, Fangyu Du, Linbo Zhou, Yajie Shi, Yang Du, Dongdong Liu, Wenjiao Sun, Meixia Zhang, Guoliang Chen STAT3 plays a vital role in maintaining the ...

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Anti-leishmanial click modifiable thiosemicarbazones: Design, synthesis, biological evaluation and in silico studies

15.04.2018 | Author(s): Mohamed G. Temraz, Perihan A. Elzahhar, Alaa El-Din A. Bekhit, Adnan A. Bekhit, Hala F. Labib, ..., European Journal of Medicinal Chemistry, 2018

Publication date: 10 May 2018 Source:European Journal of Medicinal Chemistry, Volume 151 Author(s): Mohamed G. Temraz, Perihan A. Elzahhar, Alaa El-Din A. Bekhit, Adnan A. Bekhit, Hala F. Labib, Ahmed S.F. Belal Leishmaniasis is a devastating tropical disease with limited ...

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Synthesis and biological evaluation of 2,5-disubstituted furan derivatives as P-glycoprotein inhibitors for Doxorubicin resistance in MCF-7/ADR cell

15.04.2018 | Author(s): Ya-Sheng Li, Dong-Sheng Zhao, Xing-Yu Liu, Yi-Xian Liao, Hong-Wei Jin, Gao-Peng Song, Zi-Ning ..., European Journal of Medicinal Chemistry, 2018

Publication date: 10 May 2018 Source:European Journal of Medicinal Chemistry, Volume 151 Author(s): Ya-Sheng Li, Dong-Sheng Zhao, Xing-Yu Liu, Yi-Xian Liao, Hong-Wei Jin, Gao-Peng Song, Zi-Ning Cui Multidrug resistance (MDR) is a tendency in which cells become resistant to ...

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Benzopyrroloxazines containing a bridgehead nitrogen atom as promising scaffolds for the achievement of biologically active agents

15.04.2018 | Author(s): Fedora Grande, Maria A. Occhiuzzi, Giuseppina Ioele, Gaetano Ragno, Antonio Garofalo, European Journal of Medicinal Chemistry, 2018

Publication date: 10 May 2018 Source:European Journal of Medicinal Chemistry, Volume 151 Author(s): Fedora Grande, Maria A. Occhiuzzi, Giuseppina Ioele, Gaetano Ragno, Antonio Garofalo The present review lists the papers and patents dealing with the class of polycondensed ...

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Synthesis and structure-activity relationships of quinolinone and quinoline-based P2X7 receptor antagonists and their anti-sphere formation activities in glioblastoma cells

15.04.2018 | Author(s): Seung-Hwa Kwak, Seungheon Shin, Ji-Hyun Lee, Jin-Kyoung Shim, Minjeong Kim, So-Deok Lee, Aram ..., European Journal of Medicinal Chemistry, 2018

Publication date: 10 May 2018 Source:European Journal of Medicinal Chemistry, Volume 151 Author(s): Seung-Hwa Kwak, Seungheon Shin, Ji-Hyun Lee, Jin-Kyoung Shim, Minjeong Kim, So-Deok Lee, Aram Lee, Jinsu Bae, Jin-Hee Park, Aliaa Abdelrahman, Christa E. Müller, Steve ...

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Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB)

15.04.2018 | Author(s): Giovanni Marzaro, Ilaria Lampronti, Elisabetta D'Aversa, Gianni Sacchetti, Giorgia Miolo, Chris ..., European Journal of Medicinal Chemistry, 2018

Publication date: 10 May 2018 Source:European Journal of Medicinal Chemistry, Volume 151 Author(s): Giovanni Marzaro, Ilaria Lampronti, Elisabetta D'Aversa, Gianni Sacchetti, Giorgia Miolo, Christian Vaccarin, Giulio Cabrini, Maria Cristina Dechecchi, Roberto Gambari, ...

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Design, synthesis and biological evaluation of C(4) substituted monobactams as antibacterial agents against multidrug-resistant Gram-negative bacteria

15.04.2018 | Author(s): Qunhuan Kou, Ting Wang, Feng Zou, Shuhua Zhang, Qian Chen, Yushe Yang, European Journal of Medicinal Chemistry, 2018

Publication date: 10 May 2018 Source:European Journal of Medicinal Chemistry, Volume 151 Author(s): Qunhuan Kou, Ting Wang, Feng Zou, Shuhua Zhang, Qian Chen, Yushe Yang A series of novel pyridone conjugated monobactams with various substituents at the (4) position were ...

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