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500 Aktuelle Fachpublikationen in Journal of Molecular Recognition

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Electrochemical monitoring of aflatoxin M1 in milk samples using silver nanoparticles dispersed on α‐cyclodextrin‐GQDs nanocomposite

17.01.2018 | Rana Shadjou, Mohammad Hasanzadeh, Mohammad Heidar‐poor, Nasrin Shadjou, Journal of Molecular Recognition, 2018

Abstract Aflatoxins are potential food pollutants produced by fungi. One of important toxins is aflatoxin M1 (AFM1). A great deal of concern is associated with AFM1 toxicity. In the present study, an innovative electrochemical interface for quantitation of AFM1 based on ternary signal ...

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12.01.2018 | Journal of Molecular Recognition, 2018

No abstract is available for this article.

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12.01.2018 | Journal of Molecular Recognition, 2018

No abstract is available for this article.

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Design of nonapeptide LVFFARKHH: A bifunctional agent against Cu2+‐mediated amyloid β‐protein aggregation and cytotoxicity

10.01.2018 | Huan Zhang, Chong Zhang, Xiao‐Yan Dong, Jie Zheng, Yan Sun, Journal of Molecular Recognition, 2018

Abstract Dysfunctional accumulation of amyloid β‐protein (Aβ) mediated by Cu2+ exhibits higher neurotoxicity and accelerates the progress of Alzheimer's disease, so inhibition of Cu2+‐mediated Aβ aggregation and cytotoxicity has been considered as a therapeutic strategy for the disease. ...

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Design of nonapeptide LVFFARKHH: A bifunctional agent against Cu2+‐mediated amyloid β‐protein aggregation and cytotoxicity

10.01.2018 | Huan Zhang, Chong Zhang, Xiao‐Yan Dong, Jie Zheng, Yan Sun, Journal of Molecular Recognition, 2018

Abstract Dysfunctional accumulation of amyloid β‐protein (Aβ) mediated by Cu2+ exhibits higher neurotoxicity and accelerates the progress of Alzheimer's disease, so inhibition of Cu2+‐mediated Aβ aggregation and cytotoxicity has been considered as a therapeutic strategy for the disease. ...

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Peptide selectivity between the PDZ domains of human pregnancy‐related serine proteases (HtrA1, HtrA2, HtrA3, and HtrA4) can be reshaped by different halogen probes

20.12.2017 | Mei‐Ling Sun, Li‐Mei Sun, Yong‐Qing Wang, Journal of Molecular Recognition, 2017

Abstract The human HtrA family of serine proteases (HtrA1, HtrA2, HtrA3, and HtrA4) are the key enzymes associated with pregnancy and closely related to the development and progression of many pathological events. Previously, it was found that halogen substitution at the indole moiety of ...

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09.10.2017 | Journal of Molecular Recognition, 2017

No abstract is available for this article.

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05.09.2017 | Journal of Molecular Recognition, 2017

No abstract is available for this article.

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Room temperature synthesis and binding studies of solution‐processable histamine‐imprinted microspheres

05.09.2017 | Edwin F. Romano, Clovia I. Holdsworth, Joselito P. Quirino, Regina C. So, Journal of Molecular Recognition, 2017

Abstract Accurate quantification of histamine levels in food and in biological samples is important for monitoring the quality of food products and for the detection of pathophysiological conditions. In this study, solution processable histamine‐imprinted microspheres were synthesized at 30°C ...

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Activity of Zn and Mg phthalocyanines and porphyrazines in amyloid aggregation of insulin

30.08.2017 | V. Kovalska, S. Chernii, M. Losytskyy, J. Ostapko, I. Tretyakova, A. Gorski, V. Chernii, S. Yarmoluk, Journal of Molecular Recognition, 2017

Abstract Formation of the deposits of protein aggregates—amyloid fibrils in an intracellular and intercellular space—is common to a large group of amyloid‐associated disorders. Among the approaches to develop of therapy of such disorders is the use of agents preventing protein fibrillization. ...

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